Quinolines and derivatives

Aromatic organic heterocyclic compounds that contain a benzene ring fused with a six-membered ring that contains one nitrogen atom and five carbon atoms. Includes compounds that are derived from quinolines.

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1,801 – 1,815 of 5,523 results

1,801

eMolecules 288154-18-7 | tert-Butyl 4-amino-4-carbamoylpiperidine-1-carboxylate | Ambeed | MFCD04114477 | 243.307 | C11H21N3O3 | 95.000 | CC(C)(C)OC(=O)N1CCC(N)(CC1)C(N)=O | 25g | 552739300

tert-Butyl 4-amino-4-carbamoylpiperidine-1-carboxylate | Ambeed | 288154-18-7 | MFCD04114477 | 243.307 | C11H21N3O3 | 95.000 | CC(C)(C)OC(=O)N1CCC(N)(CC1)C(N)=O | 25g | 552739300

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1,802

eMolecules 88950-64-5 | 1-Aminocyclopropane-1-carboxylic acid, N-BOC protected | Apollo Scientific | MFCD00083257 | 201.222 | C9H15NO4 | 97.000 | CC(C)(C)OC(=O)NC1(CC1)C(O)=O | 5g | 600855396

1-Aminocyclopropane-1-carboxylic acid, N-BOC protected | Apollo Scientific | 88950-64-5 | MFCD00083257 | 201.222 | C9H15NO4 | 97.000 | CC(C)(C)OC(=O)NC1(CC1)C(O)=O | 5g | 600855396

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1,803

eMolecules 72716-87-1 | 2-methoxypyridine-4-carbaldehyde | Pharmablock | MFCD06410680 | 137.138 | C7H7NO2 | 97.000 | COc1cc(C=O)ccn1 | 50mg | 551201751

2-methoxypyridine-4-carbaldehyde | Pharmablock | 72716-87-1 | MFCD06410680 | 137.138 | C7H7NO2 | 97.000 | COc1cc(C=O)ccn1 | 50mg | 551201751

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1,804

Aobchem 2-Fluoro-5-(morpholine-4-carbonyl)phenylboronic acid | ≥97% | CAS 1072951-41-7 | C11H13BFNO4 | 5g

2-Fluoro-5-(morpholine-4-carbonyl)phenylboronic acid | ≥97% | CAS 1072951-41-7 | C11H13BFNO4 | 5g

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1,805

eMolecules 74124-79-1 | N,N'-DISUCCINIMIDYL CARBONATE | AstaTech | MFCD00009767 | 256.170 | C9H8N2O7 | 95.000 | O=C(ON1C(=O)CCC1=O)ON1C(=O)CCC1=O | 100g | 490832455

N,N'-DISUCCINIMIDYL CARBONATE | AstaTech | 74124-79-1 | MFCD00009767 | 256.170 | C9H8N2O7 | 95.000 | O=C(ON1C(=O)CCC1=O)ON1C(=O)CCC1=O | 100g | 490832455

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1,806

Apexbio Technology LLC Fluocinolone Acetonide 67-73-2 200mg

Fluocinolone Acetonide (67-73-2) is a glucocorticoid receptor (GR) agonist targeting the GR It is designed to modulate intracellular signaling pathways mediated by the GR thereby regulating inflammatory response and influencing lipid metabolism by reducing lipid accumulation in tissues Fluocinolone Acetonide exerts its biological activity primarily through activation of the GR In cellular assays Fluocinolone Acetonide demonstrates stimulation of proliferation in dental pulp cells (DPCs) Based on these pharmacological properties Fluocinolone Acetonide holds research potential in studies of dental tissue regeneration and repair as well as in investigations of preventative and therapeutic strategies for chemotherapy-induced peripheral neuropathy

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1,807

Medchemexpress LLC Z-LYS-SBZL monohydrochloride | 69861-89-8 | 99.7% | C21H27ClN2O3S | 25 MG

Z-LYS-SBZL monohydrochloride (α-N-Carbobenzoxy-L-lysine thiobenzyl ester monohydrochloride) is a lysine derivative primarily intended for research use. Amino acids and their derivatives, like this product, are recognized as beneficial ergogenic dietary substances. It is designed to support various biological activities related to physical and mental performance.

Influences anabolic hormone secretion
Supplies fuel during exercise
Enhances mental performance during stress-related tasks
Prevents exercise-induced muscle damage
For research use only

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1,808

Aobchem 2 4-Dimethylthiophene-3-carbaldehyde | ≥97% | CAS 63826-85-7 | C7H8OS | 250mg

2 4-Dimethylthiophene-3-carbaldehyde | ≥97% | CAS 63826-85-7 | C7H8OS | 250mg

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1,809

Apexbio Technology LLC SR-9243 1613028-81-1 200mg

SR-9243 (CAS 1613028-81-1) is a small-molecule inverse agonist targeting liver X receptors (LXRs) nuclear transcription factors involved in metabolic regulation It is designed to induce LXR corepressor interactions thereby suppressing transcriptional activation of glycolytic and lipogenic enzyme genes SR-9243 exerts its biological activity primarily through inhibition of glycolysis- and lipid biosynthesis-associated gene expression In in vitro assays SR-9243 reduces cancer cell viability and induces apoptosis through caspase 3/7 activation in colorectal cancer cell lines Based on these pharmacological properties SR-9243 holds research potential in investigating metabolic reprogramming in cancer particularly in prostate colon and lung cancer models

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1,810

Apexbio Technology LLC LDK378 1032900-25-6 200mg

LDK378 (CAS 1032900-25-6) is a potent inhibitor of anaplastic lymphoma kinase (ALK) a receptor tyrosine kinase within the insulin receptor superfamily It exhibits an in vitro IC50 of 200 pM for ALK and displays moderate to high inhibitory activity against a limited set of other kinases including IGF-1R (IC50 8 nM) InsR (IC50 7 nM) and STK22D (IC50 23 nM) LDK378 suppresses proliferation of Ba/F3 cells transfected with NPM-ALK fusion and Karpas 299 human lymphoma cells harboring NPM-ALK with IC50 values of 22 8 nM and 26 nM respectively The compound is widely used in preclinical studies to investigate ALK-driven signaling and its potential as a therapeutic target in oncology

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1,811

Medchemexpress LLC Targocil | 1200443-21-5 | 99.3% | 475.95 | 200 MG

Targocil is a bacteriostatic inhibitor of wall teichoic acid (WTA) biosynthesis. It is effective against both methicillin-susceptible S. aureus (MSSA) and methicillin-resistant S. aureus (MRSA) strains, with MIC90s of 2 μg/mL for both. It shows excellent activity against S. aureus isolates from bacterial keratitis.

Bacteriostatic inhibitor of wall teichoic acid (WTA) biosynthesis
Inhibits growth of methicillin-susceptible S. aureus (MSSA)
Inhibits growth of methicillin-resistant S. aureus (MRSA)
Effective against S. aureus strains Newman, MW2, MG2375, and MG2389
Low toxicity for HCECs at 5 μg/mL after 24 h exposure

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1,812

Medchemexpress LLC Corticosterone | 50-22-6 | 99.8% | 200 MG

Corticosterone is an orally active glucocorticoid produced by the adrenal cortex. It is involved in regulating neuronal functions within the limbic system, including the hippocampus, prefrontal cortex, and amygdala.

Enhances Rab-mediated AMPAR membrane traffic through SGK-induced phosphorylation of GDI.
Has an immunosuppressive effect by interfering with dendritic cell maturation.

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1,813

Apexbio Technology LLC Epalrestat 82159-09-9 200mg

Epalrestat (CAS 82159-09-9) is an orally available inhibitor of aldose reductase the rate-limiting enzyme of the polyol pathway involved in glucose metabolism By suppressing aldose reductase activity epalrestat limits intracellular sorbitol accumulation in neural tissues a process implicated in diabetic complications This compound is frequently employed in experimental models of diabetic neuropathy to investigate how modulation of the polyol pathway affects disease pathology and cellular signaling Epalrestat thus serves as a valuable molecular tool for elucidating the pathophysiology and pharmacology relevant to diabetes-associated neuronal damage

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1,814

Medchemexpress LLC Sapitinib | 848942-61-0 | 200 MG

Sapitinib (AZD-8931) is a reversible, ATP competitive EGFR inhibitor with IC50s of 4, 3, and 4 nM for EGFR, ErbB2, and ErbB3 in cells, respectively. It demonstrates potent inhibitory effects on erbB2 in ligand-independent MCF-7 cl24 cells, significantly inhibits Akt phosphorylation, and induces apoptosis in human IBC cells.

Reversible, ATP competitive EGFR inhibitor
Potent inhibitory effect on erbB2 in ligand-independent MCF-7 cl24 cells
Significantly inhibits phosphorylation of Akt in SUM149 and FC-IBC-02 cells
Inhibits proliferation and induces apoptosis in human IBC cells
Active in xenograft tumor models responsive to EGFR inhibition alone or EGFR or erbB2 inhibition
Causes pharmacodynamic changes in proliferation and apoptosis markers in human tumor xenograft models
Favorable oral pharmacokinetics in rat and dog
Low human hepatocyte turnover

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1,815

eMolecules 36404-88-3 | 2-CHLORO-PYRIDINE-3-CARBALDEHYDE | AstaTech | MFCD01315308 | 141.550 | C6H4ClNO | 97.000 | Clc1ncccc1C=O | 100g | 206680064

2-CHLORO-PYRIDINE-3-CARBALDEHYDE | AstaTech | 36404-88-3 | MFCD01315308 | 141.550 | C6H4ClNO | 97.000 | Clc1ncccc1C=O | 100g | 206680064

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Quinolines and derivatives

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Medchemexpress LLC Z-LYS-SBZL monohydrochloride | 69861-89-8 | 99.7% | C21H27ClN2O3S | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Targocil | 1200443-21-5 | 99.3% | 475.95 | 200 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Corticosterone | 50-22-6 | 99.8% | 200 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Sapitinib | 848942-61-0 | 200 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Z-LYS-SBZL monohydrochloride | 69861-89-8 | 99.7% | C21H27ClN2O3S | 25 MG

Medchemexpress LLC Targocil | 1200443-21-5 | 99.3% | 475.95 | 200 MG

Medchemexpress LLC Corticosterone | 50-22-6 | 99.8% | 200 MG

Medchemexpress LLC Sapitinib | 848942-61-0 | 200 MG